業績

著書および訳書

町田千代子・岩川秀和・小島晶子 左右相対称で扁平な葉がつくられる分子メカニズムを探る「解説」バイオインダストリー Vol.65 No.4 16-20, 2007

葉の形造りにおける左右相対称性と扁平性　町田千代子・上野直人・小島晶子・町田泰則　学術月報　58, 6-11, 2005

小島晶子・町田千代子　植物形態形成における体軸決定の仕組み「発生システムのダイナミクス」（編集：上野直人・八杉貞雄・野地澄晴）「蛋白質・核酸・酵素」増刊号 50, 724-730, 2005

Machida C., Iwakawa, H., Ueno, Y., Semiarti, E., Tsukaya, H., Hasebe, M．Kojima, S. and Machida, Y.　"Morphogenesis and Pattern Formation in Biological Systems - Experiments and Models -" edited by T. Sekimura, S. Noji, N. Ueno, and P.K. Maini. Published by Springer-Verlag Tokyo, pp177-187, 2003

学術論文、評論

Iwasaki M., Takahashi H., Iwakawa H., Nakagawa A., Ishikawa T., Tanaka h., Matsumura Y., Pekker I., Eshed Y., Vial-Pradel S., Ito T., Watanabe Y., Ueno Y., Fukazawa H., Kojima S., Machida Y. and Machida C.: Dual regulation of ETTIN (ARF3) gene expression by AS1-AS2, which maintains the DNA methylation level, is involved in stabilization of leaf adaxial-abaxial partitioning in Arabidopsis. Development 140, 1958-1969 (2013)

Takahashi H., Iwakawa H., Ishibashi N., Iwasaki, M., Kojima S., Matsumura Y., Prananingrum P., Takahashi A., Ikezaki M., Luo, L., Kobayashi T., Machida Y. and Machida C. Meta-analyses of microarrays of Arabidopsis asymmetric leaves2 (as2) and as1 mutants reveal a critical role of the ETT pathway in stabilization of adaxial-abaxial patterning and cell division during leaf development. Plant Cell Physiol 54(3), 418-431 (2013)

Takahashi H., Nakagawa A., Kojima S., Takahashi A., Cha B. Y., Woo J., Nagai K., Machida Y. and Machida C.: Discovery of novel rules for G-quadruplex-forming sequences in plants by using bioinformatics methods J. Bioscience and Bioengineering 114, 570-575 (2012)

Nakagawa A., Takahashi H., Kojima S., Sato N., Ohga K., Cha B. Y., Woo J., Nagai K., Horiguchi G., Tsukaya H., Machida Y. and Machida C.: Berberine enhances defects in the establishment of leaf polarity in asymmetric leaves1 and asymmetric leaves2 of Arabidopsis thaliana. Plant Molecular Biology 79, 569-581 (2012)

Keta S., Iwakawa I., Ikezaki M.,Semiarti E., Kojima S., Machida Y. and Machida C.: Roles of the ASYMMETRIC LEAVES2 gene in floral organ development in Arabidopsis thalianav. Plant Biotechnology 29, 1-8 (2012)

Ishibashi N., Kanamaru K., Ueno Y., Kojima S., Kobayashi T., Machida C. and Machida Y.: ASYMMETRIC-LEAVES2 and an ortholog of eukaryotic NudC domain proteins repress expression of AUXIN-RESPONSE-FACTOR and class 1 KNOX homeobox genes for development of flat symmetric leaves in Arabidopsis Biology Open 1, 197-207 (2012)

Kojima S., Iwasaki, M., Takahashi H., Imai, T., Matsumura, Y., Fleury D., Van Lijsebettens, M., Machida Y. and Machida C.: ASYMMETRIC LEAVES2 and Elongator, a Histone Acetyltransferase Complex, Mediate the Establishment of Polarity in Leaves of Arabidopsis thaliana Plant Cell Physiol. 52(8), 1259-1273 (2011)

Ikezaki M., Kojima M., Sakakibara H., Kojima S., Ueno Y., Machida C., Machida Y.: Genetic networks regulated by ASYMMETRIC LEAVES1 (AS1) and AS2 in leaf development in Arabidopsis thaliana: KNOX genes control five morphological events. Plant J. 61, 70-82 (2010)

Iwakawa H., Iwasaki M., Kojima S., UenoY., Soma T., Tanaka H., Semiarti E., Machida Y. and Machida C.: Expression of the ASYMMETRIC LEAVES2 gene in the adaxial domain of Arabidopsis leaves represses cell proliferation in this domain and is critical for the development of properly expanded leaves. Plant J. 51, 173-184 (2007)

Iwakawa H., Ueno Y, Semiarti E., Onouchi H., Kojima S., Tsukaya H., Hasebe Y., Soma T., Ikezaki M., Machida C., and Machida Y.: The ASYMMETRIC LEAVES2 gene of Arabidopsis thaliana, required for formation of a symmetric flat leaf lamina, encodes a member of a novel family of proteins characterized by cysteine repeats and a leucine zipper. Plant and Cell Physiology 43, 467-478 (2002)

Kojima S., Takahashi, Y., Kobayashi, Y., Monna, L., Sasaki, T., Araki, T. and Yano, M.: Hd3a, a rice ortholog of the Arabidopsis FT gene, promotes transition to flowering downstream of Hd1 under short-day conditions. Plant Cell Physiol. 43, 1096-1105 (2002)

Monna L., Lin H. X., Kojima S., Sasaki T. and Yano M.: Genetic dissection of genomic region for a quantitative trait locus, Hd3 into two loci, Hd3a and Hd3b , controlling heading date in Rice. Theor. Appl. Genet. 104, 772-778 (2002)

Yano M., Kojima S., Takahashi Y. and Lin H. X.: Genetic control of flowering in rice, a short-day plant. Plant Physiol. 127, 1425-1429 (2001)

Kojima S., Banno H., Yoshioka Y., Oka A., Machida C., and Machida Y.: A binary vector plasmid for gene expression in plant cells that is stably maintained in agrobacterium cells. DNA research 6, 407-410 (1999)

Shinozuka Y, Kojima S., Shomura A., Ichimura H., Yano M., Yamamoto K. and Sasaki T.: Isolation and characterization of rice MADS box gene homologues and their RFLP mapping. DNA Res. 6, 123-129 (1999)

Yoshioka Y., Matsumoto S., Kojima S., Ohshima K., Okada N. and Machida, Y.: Molecular characterization of a short interspersed repetitive element (SINE) from tobacco that exhibits sequence homology to specific tRNAs. Proc. Natl. Acad. Sci. USA. 90, 6562-6566 (1993)

講演、シンポジウム、学会発表

シロイヌナズナの葉の形態形成に関わるasymmetric leaves2亢進変異体#27のクローニング, 日本植物生理学会第50回年会, 2009

シロイヌナズナのAS2による葉の背軸化遺伝子ETT/ARF3制御機構の解析 日本植物生理学会第50回年会, 2009

Semiarti, E., Indrianto, A., Purwantoro, A., Isminingsih, S., Suseno, N., Machida, Y., Kojima, S. and Machida, C.: Development of methods for Agrobacterium-mediated transformation of the wild orchid species Phalaenopsis amabilis and its application.　 Nagoya International Orchid Congress, 2009

シロイヌナズナの葉の発生分化に関わるAS2、AS1 による新規遺伝的ネットワークの解明, 日本遺伝子学会第80回大会, 2008

シロイヌナズナの葉の極性の確立におけるAS2 によるETT/ARF3 制御機構の解析, 日本遺伝子学会第80回大会, 2008

シロイヌナズナのAS2遺伝子による葉の表裏の極性に関わるETT/ARF3の制御機構の解析, 第10回RNAミーティング, 2008

Iwasaki, M., Kojima, S., Matsumura, Y., Ueno, Y., Machida, Y. and Machida, C. 2008.　A genetic screen for genes interacting with AS2 during leaf development. 19th International Conference on Arabidopsis Reseach, at Montreal, Canada

シロイヌナズナの葉の発生に関わる asymmetric leaves 2 の亢進変異体の解析,日本植物生理学会第49回年会, 2008

シロイヌナズナのASYMMETRIC LEAVES2 (AS2)遺伝子とともに葉の形態形成に関わる遺伝子の解析, 日本分子生物学会第30回大会, 2007

葉の向背軸形成におけるAS2によるARF3/ETTの制御系の解析, 日本植物学会第71回大会, 2007

Iwakawa H., Iwasaki M., Kojima S., Takahashi H., Kobayashi T., Machida Y. and Machida C., The ASYMMETRIC LEAVES2 gene regulates adaxial cell proliferation involved in the development of symmetric and flat leaf laminae. 18th International Conference on Arabidopsis Reseach, June, 2007 (Beijing, CHN).

Iwasaki M., Iwakawa H., Ueno Y., Takahashi H., Kojima S., Kobayashi T., Machida Y. and Machida C. The ASYMMETRIC LEAVES2 regulates leaf polarity by repressing ETTIN in Arabidopsis. 18th International Conference on Arabidopsis Reseach, June, 2007 (Beijing, CHN).

シロイヌナズナの葉の形態形成に関わるasymmetric leaves2(as2)亢進変異体のスクリーニング, 日本分子生物学会2006フォーラム, 2006

マイクロアレイ解析による扁平で左右対称的な葉の形成に関わる遺伝子の探索, 日本分子生物学会2006フォーラム, 2006

Kojima S., Matsumura Y.,Ueno Y., Machida Y. and Machida C.: A genetic screen for new factors involved in ASYMMETRIC LEAVES2-mediated leaf developmental pathway. The 20th IUBMB Congress and 11th FAOBMB Congress, June , 2006 ( Kyoto, Japan).

Kojima S., Ueno Y., Iwakawa H., Semiarti E., Soma T., Tsukaya H., Ishikawa T., Machida Y. and Machida C. : ”The ASYMMETRIC LEAVES2 is involved in the formation of a flat leaf lamina in the presence of the ASYMMETRIC LEAVES1 gene”, 16th International Conference on Arabidopsis Reseach, Univ. of Wisconsin, June 2005 (Madison, USA)

Kojima S., Iwakawa H., Ueno Y., Semiarti E., Soma T., Kuzumaki A.,Tsukaya H., Machida C. and Machida Y. : Function of the ASYMMETRIC LEAVES1 and ASYMMETRIC LEAVES2 genes in leaf development of Arabidopsis. International symposium on PLANT AXIS FORMATION AND SIGNAL TRANSDUCTION, March, 2005 (Tokyo , Japan).

日本植物生理学会論文賞受賞講演：イネの花成制御における Hd3a 遺伝子の機能, 日本植物生理学会2004年度年会, 2004

Map-based cloning of the rice photoperiod sensitivity QTL, Hd3a, Plant and Animal Genome IX Conference, 2001

Cataloguing of Rice cDNA Clones, 50th SEB Symposium-Unifying Plant Genomes, 1995

受賞

The 80th Annual Meeting of Genetics Society of Japan Best Paper Award 2008 Machida C., Iwakawa H., Takahashi H., Mazet Rémi, Iwasaki M., Kojima S., Kobayashi T. and Machida Y. : Analysis of genetic network of gene regulation mediated by AS2 and AS1 in the leaf development in Arabidopsis thaliana September 2009 (Nagoya)

Nagoya International Orchid Congress（NIOC）Encouragement Award 2009, Semiarti, E., Indrianto, A., Purwantoro, A., Isminingsih, S., Suseno, N., Machida, Y., Kojima, S. and Machida, C.：Development of methods for Agrobacterium-mediated transformation of the wild orchid species Phalaenopsis amabilis and its application. Nagoya International Orchid Congress 2009 (Nagoya)

日本植物生理学会論文賞: イネの花成制御における Hd3a 遺伝子の機能, 日本植物生理学会(2004)

その他

特許：矢野昌裕、山本伸一、小島晶子、高橋裕治、植物の開花促進遺伝子RFT1および植物の開花時期を予測する方法、特許第3823137 (2006年7月)

研究費採択状況

科学研究費補助金

2013-2015　基盤（C）研究代表者

2010-2012　基盤（C）研究代表者

2009-2011　基盤（C）連携研究者（代表 町田千代子）

2007-2008　基盤（C）連携研究者（代表 町田千代子）

2005-2007　若手（B）研究代表者